منابع مشابه
Cavitary Lung Lesions in a Difficult-To-Treat Asthma Patient.
We describe an interesting case of severe asthma who was not showing satisfactory response to standard treatment. Investigations revealed him to be suffering from allergic bronchopulmonary aspergillosis (ABPA). After starting systemic steroids he showed marked improvement initially only to have recurrent symptoms within a year. He was investigated further and found to have chronic pulmonary asp...
متن کاملTargeting Interferon- to Treat Atherosclerosis
The chronic inflammatory nature of atherosclerotic disease is now widely appreciated. Abnormal deposition and oxidative modification of serum lipoproteins in arterial walls stimulates the recruitment of monocytes and their conversion into foam cells. Concurrently, both innate and adaptive immune responses are induced. Cytokines and growth factors produced as part of these responses lead to the ...
متن کاملVisualizing Particulate Antigen Targeting to Dendritic Cells (DCs) In vitro
In this study, Ealpha green fluorescence protein (EαGFP)/YAe system was used to visualize antigen uptake and presentation by BMDCs [12,14] (Figure 1). This system allows assessment of antigen uptake/degradation and, in combination with the YAe antibody antigen presentation in situ [12,14,15]. When this antigen is internalized by DCs, EαGFP is degraded and the Eα peptide is presented by IAbMHCII...
متن کاملHow to treat an asthma attack.
What are the symptoms? You may have any of the following: • Shortness of breath, trouble breathing, or fast breathing • Trouble doing normal activities, such as exercising, playing sports, or doing chores that involve lifting • Trouble talking • Fingers or lips turning blue or gray • A peak flow rate (how fast you can blow air out of your lungs) less than 80 percent of your personal best • Tigh...
متن کاملSystematic assessment of difficult-to-treat asthma.
Five per cent of asthmatics remain symptomatic despite high-dose treatment. The aim of the study was to investigate how often such difficult-to-treat asthma is due to intractable asthma, misdiagnosis, non-adherence with therapy, or psychiatric problems. Difficult asthma was defined as persistence of symptoms despite treatment at step 4 of British guidelines or requirement for long-term oral glu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2006
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri1987